b'Controls | DNA ControlsControls, Reagents, Controls, Reagents,and Enzymes and EnzymesDNA ControlsDNA Controls DNA Controls Cell Line DNAEvery laboratory needs suitable controls (positive and negative) forInvivoscribe offers a multitude of high quality, reliable DNA controls sensitivity and proficiency testing, as well as for troubleshooting. manufactured under cGMP conditions.Since patient samples cannot serve as true controls (due to a lack ofReliable Positive Controls IVS-0007 Clonal Control DNAcharacterization and inter-sample variability), These controls can be used for most assays targeting B- and T-cellCell Line DNA controls are extracted from established cellIVS-0007 Clonal Control DNA can be used as a positive control for:antigen receptor loci, FLT3 ITD and TKD loci, or IGH-BCL2, BCR-ABL1, andlines grown under cell culture conditions recommended by the Gene Rearrangements:IGH, IGK, IGLQuick Reference for DNA ControlsPML-RARa chromosome translocations. supplier. Our controls are tested extensively to ensure quality andChromosome Translocations:IGH-BCL2 t(14;18) Mbrreproducibility of your test results. Please note, these controls are forMutations:n/cThe vast majority of our high-quality DNA controls, including sensitivity controls and panels, are supplied in aliquots of 100 L and arequalitative use only.This control is also available as several ready-to-use dilutions into a adjusted to a final concentration of 200 g/mL in 1/10 TE (1 mM Tris- HCl (pH 8.0), 0.1 mM EDTA). Note: n/c is used to indicate that the control has not beenstandard negative control as listed in the table below.ImmunoglobulinT-Cell Receptor Genefully characterized; there may be additional rearrangements,Catalog # DescriptionPositive for Rearrangements Mutations Translocations Rearrangements translocations or mutations associated with the control. 4-088-0370 100% IVS-0007 Clonal Control DNA*IGHIGK IGL IGHV SHM FLT3 ITD FLT3 TKD IGH-CCND1** IGH-BCL2 TRB TRG TRD 4-088-0390 20% IVS-0007 Clonal Control DNAStandard Concentrations 4-088-0400 10% IVS-0007 Clonal Control DNAIVS-0001 u The majority of our high-quality DNA controls, including our4-088-0410 5% IVS-0007 Clonal Control DNAIVS-0004 u u sensitivity panels, are supplied in aliquots of 100 L and are4-088-0420 1% IVS-0007 Clonal Control DNAIVS-0007 u u u u adjusted to a final concentration of 200 g/mL in 1/10 TE (1 mM Tris- *These controls are general purpose reagents (GPRs). All others are researchIVS-0008 m u u HCl (pH 8.0), 0.1 mM EDTA). This diluent provides sufficient bufferinguse only (RUO).IVS-0009 u u capacity and EDTA to protect the DNA controls without interfering IVS-0010 u u u with the Mg 2+concentrations required for robust amplification IVS-0013 u u reactions. DNA dilutions are diluted volume to volume (v/v) in ourIVS-0008 Clonal Control DNAnegative control DNA, IVS-0000 Polyclonal Control DNA.IVS-0019 u u IVS-0008 Clonal Control DNA can be used as a positivecontrol for: IVS-0021 u u u u Gene Rearrangements:IGH D H -J H, TRB, TRGIVS-0024 u u Chromosome Translocations:n/cIVS-0029 u u IVS-0001 Clonal Control DNA Mutations:n/c IVS-0030 u u u IVS-0001 Clonal Control DNA can be used as a positive control for: This control is also available as several ready-to-use dilutions into a IVS-0031 u u Gene Rearrangements:n/cstandard negative control as listed in the table below. IVS-P002 Chromosome Translocations:IGH-BCL2 t(14;18) mcrCatalog # DescriptionLymphoQuant B-cell Internal Control Mutations:n/c 4-088-0430 100% IVS-0008 Clonal Control DNA*LymphoQuant T-cell Internal Control Catalog # Description 4-088-0460 10% IVS-0008 Clonal Control DNALymphoTrack B-cell Low Positive Control 4-088-0010 100% IVS-0001 Clonal Control DNA* 4-088-0470 5% IVS-0008 Clonal Control DNALymphoTrack T-cell Low Positive Control 4-088-0480 1% IVS-0008 Clonal Control DNAFLT3 ITD Positive Control u IVS-0004 Clonal Control DNAFLT3 TKD Positive Control u IVS-0004 Clonal Control DNA can be used as a positive control for: IVS-0009 Clonal Control DNAu Gene rearrangement m Partial IGH DH-JH rearrangementRecommended for NGS Gene Rearrangements:TRB, TRG IVS-0009 Clonal Control DNA can be used as a positive control for: This c ontrol does not contain a complete IGH VH-JH rearrangement and may only These c ontrols can be used as SHM positive controls with 2% mutational ratesChromosome Translocations:n/cbe suitable for IGH DH-JH rearrangements. compared to the germline sequence. Gene Rearrangements:TRB, TRG ** IGH-CCND1 was previously referred to as BCL1/JHMutations:n/cChromosome Translocations:n/c This control is also available as several ready-to-use dilutions into aMutations:n/cTissue DNA standard negative control as listed in the table below.This control is also available as several ready-to-use dilutions into a Standard Concentrations IVS-0000 Polyclonal Control DNA Catalog # Description standard negative control as listed in the table below.The vast majority of our high-quality DNA controls, includingTissue DNA controls are extracted from normal, disease-free tissue4-088-0190 100% IVS-0004 Clonal Control DNA* Catalog # Descriptionsensitivity controls and panels, are supplied in aliquots of 100 Land are tested extensively to ensure quality and reproducibility of your4-088-0210 20% IVS-0004 Clonal Control DNA 4-088-0490 100% IVS-0009 Clonal Control DNA*and are adjusted to a final concentration of 200 g/mL in 1/10 TE test results. IVS-0000 Polyclonal Control DNA consists of genomic DNA4-088-0220 10% IVS-0004 Clonal Control DNA 4-088-0500 30% IVS-0009 Clonal Control DNA(1 mM Tris- HCl (pH 8.0), 0.1 mM EDTA). This diluent providesisolated from the tissue of normal human tonsils. This control represents4-088-0510 20% IVS-0009 Clonal Control DNAsufficient buffering capacity and EDTA to protect the DNA withoutan excellent negative control for gene rearrangements, chromosome4-088-0230 5% IVS-0004 Clonal Control DNA 4-088-0520 10% IVS-0009 Clonal Control DNAinterfering with the Mg 2+concentrations required for robusttranslocations, and mutation tests and is included in all of our PCR4-088-0530 5% IVS-0009 Clonal Control DNAamplification reactions. DNA-based assay kits. This DNA is supplied at a volume of100 L and at a concentration of 200 g/mL. 4-088-0540 1% IVS-0009 Clonal Control DNA Catalog # Description1324-092-0010 IVS-0000 Polyclonal Control DNA* Invivoscribe 2021|133'