b'Minimal Residual Disease (MRD) Solution | Research Use Only (RUO)MRD Software Minimal Residual Disease (MRD) SolutionLymphoTrack Minimal Residual Disease(MRD) SoftwareSoftware Use The provided software is composed of three distinct parts: The LymphoTrack MRD Bioinformatics Software package is provided1.A bioinformatics Data Analysis Applicationwith each LymphoTrack Assay upon request to aid in the evaluation2. A Project Planner that can be used to calculate confidence based of treatment response in many lymphoid malignancies such as Acute Lymphoblastic Leukemia and Multiple Myeloma to minimize theon read depth, replicate count, and DNA inputrisk of patients relapsing. The exceptional sensitivity and precision3. PDF report identifying the clonotype sequence if present and of NGS-based MRD tracking can accelerate clinical trials and drugsummarizing the degree of mismatches, calculating the read development. This MRD software is intended to detect the presencefrequency and the degree of confidence if a certain clonotype of clonotype sequences within the output files generated using theis not present at sensitivities of 10 -3 , 10 -4 , 10 -5 , and 10 -6 .Invivoscribe LymphoTrack Assays and accompanying LymphoTrack bioinformatics software; it is not intended to define the significance of these findings. Once a specific rearrangement sequence (theMinimum Software Requirementsclonotype) has been identified in a primary sample, the MRD softwareProcessor: Intel Core 2 Duo or newer CPU recommendedenables streamlined tracking of clonal populations at a sensitivity of -4 Hard Drive: At least 1 GB of free disk space is required; 2 GB 10 , or even lower limits provided sufficient DNA is tested. The MRD software can also be used for simultaneous objective tracking ofrecommendedbi-allelic sequences across multiple replicates for longitudinal subjectRAM: 4 GB required; 8 GB or more recommendedtracking and in drug development studies. Operating System: Windows 7 (64-bit) A CD-ROM drive** If a CD-ROM drive is not available, please contact us at: support@invivoscribe.comMRD Project PlannerThe Project Planner can be used to calculate the confidence of a true negative by adding replicate counts, resequencing counts, sequencing depth, and DNA input amount. The software assumes that the same sequencing depth and DNA input is used for each replicate.Research Use Only (RUO) assays are not for sale in Europe and other global markets where equivalent CE-IVD assays are available and registered with the appropriate regulatory agencies.52'