b'IGHV Leader Somatic Hypermutation Assay Next-Generation Sequencing (NGS) | CE-IVD AssaysReagents - MiSeq DetectionKit A Components Panel Components(includes all master mixes from Kit A plus the items below)Master Mix Name Index # Master Mix Name Index # Master Mix Name Index #IGH Leader MiSeq 01 A001 IGH Leader MiSeq 09 A009 IGH Leader MiSeq 18 A018IGH Leader MiSeq 02 A002 IGH Leader MiSeq 10 A010 IGH Leader MiSeq 19A019IGH Leader MiSeq 03 A003 IGH Leader MiSeq 11 A011 IGH Leader MiSeq 20 A020IGH Leader MiSeq 04 A004 IGH Leader MiSeq 12 A012 IGH Leader MiSeq 21 A021IGH Leader MiSeq 05 A005 IGH Leader MiSeq 13 A013 IGH Leader MiSeq 22 A022IGH Leader MiSeq 06 A006 IGH Leader MiSeq 14 A014 IGH Leader MiSeq 23 A023IGH Leader MiSeq 07 A007 IGH Leader MiSeq 15 A015 IGH Leader MiSeq 25 A025IGH Leader MiSeq 08 A008 IGH Leader MiSeq 16 A016 IGH Leader MiSeq 27 A027Controls ControlsIGH SHM POS (+) Qty. 1 IGH SHM POS (+) Qty. 3IGH POS (+) Qty. 1 IGH POS (+) Qty. 3NGS NEG (-) Qty. 1 NGS NEG (-) Qty. 3Merge% TotalCumulative Mutation rate In-frameNo stop Rank Sequence Length count V-gene J-gene reads %partial V-gene(Y/N) codon V-coverage(%) (Y/N)1 TTCTCGTGGTG 455 29603 IGHV4-59_08 IGHJ4_02 9.93 9.93 11.26 Y Y 98.632 CTCGCCCTCCT 463 205 IGHV5-51_01 IGHJ4_02 0.07 9.99 0.00 Y Y 99.663 GGTTTTCCTTG 484 201 IGHV3-7_01 IGHJ4_02 0.07 10.06 7.77 Y Y 100.004 CTCGCCCTCCT 463 185 IGHV5-51_01 IGHJ5_02 0.06 10.12 6.08 Y Y 99.325 CTCGCCCTCCT 469 170 IGHV5-51_01 IGHJ4_02 0.06 10.18 0.00 Y Y 99.326 CTCGCCCTCCT 466 160 IGHV5-51_01 IGHJ4_02 0.05 10.23 0.00 Y Y 99.667 CTGCTGCTGAC 460 159 IGHV2-5_10 IGHJ5_02 0.05 10.29 8.08 Y Y 97.648 GGTTTTCCTTG 493 156 IGHV3-48_02 IGHJ6_02 0.05 10.34 3.72 Y Y 98.999 CTCGCCCTCCT 334 153 IGHV5-51_02 IGHJ2_01 0.05 10.39 3.72 Y N 27.7010 CTCGCCCTCCT 334 152 IGHV5-51_02 IGHJ2_01 0.05 10.44 3.38 Y N 26.01Example Data. The top 10 sequences from a read summary generated by the LymphoTrack Dx Software - MiSeq with the SHM mutation rate and predictions pertaining to whether a sequence is in-frame or contains a premature stop codon are depicted. To learn more about the LymphoTrack Dx software, please refer to the LymphoTrack Dx Bioinformatics Software section.Ordering InformationCatalog # Products Quantity Components9-121-0059 LymphoTrackDx IGHV Leader Somatic Hypermutation Assay Kit A - MiSeq 8 indices - 5 sequencing reactions each9-121-0069 LymphoTrackDx IGHV Leader Somatic Hypermutation Assay Panel - MiSeq 24 indices - 5 sequencing reactions each9-500-0009 LymphoTrackDx Software - MiSeq 1 CD complimentary with purchaseThese products are CE-IVD assays for in vitro diagnostic use.Invivoscribe 2020|21'