b'Controls | DNA ControlsControls, Reagents, Controls, Reagents,and Enzymes and EnzymesDNA Controls DNA ControlsEvery laboratory needs suitable controls (positive and negative) forInvivoscribe offers a multitude of high quality, reliable DNA controls sensitivity and proficiency testing, as well as for troubleshooting. manufactured under cGMP conditions.Since patient samples cannot serve as true controls (due to a lack of characterization and inter-sample variability), These controls can be used for most assays targeting B- and T-cell antigen receptor loci, FLT3 ITD and TKD loci, or IGH-BCL2, BCR-ABL1, and Quick Reference for DNA ControlsPML-RARa chromosome translocations.The vast majority of our high-quality DNA controls, including sensitivity controls and panels, are supplied in aliquots of 100 L and are adjusted to a final concentration of 200 g/mL in 1/10 TE (1 mM Tris- HCl (pH 8.0), 0.1 mM EDTA).Positive for ImmunoglobulinMutations Translocations T-Cell Receptor Gene Rearrangements RearrangementsIGHIGK IGL IGHV SHM FLT3 ITD FLT3 TKD IGH-CCND1** IGH-BCL2 TRB TRG TRDIVS-0001 uIVS-0004 u uIVS-0007 u u u uIVS-0008m u uIVS-0009 u uIVS-0010 u u uIVS-0013 u uIVS-0019 u uIVS-0021 u u u uIVS-0024 u uIVS-0029 u uIVS-0030 u u uIVS-0031 u uIVS-P002LymphoQuant B-cell Internal ControlLymphoQuant T-cell Internal ControlLymphoTrack B-cell Low Positive ControlLymphoTrack T-cell Low Positive ControlFLT3 ITD Positive Control uFLT3 TKD Positive Control uu Gene rearrangement m Partial IGH DH-JH rearrangementRecommended for NGS This c ontrol does not contain a complete IGH VH-JH rearrangement and may only These c ontrols can be used as SHM positive controls with 2% mutational rates be suitable for IGH DH-JH rearrangements. compared to the germline sequence.** IGH-CCND1 was previously referred to as BCL1/JH Tissue DNAStandard Concentrations IVS-0000 Polyclonal Control DNAThe vast majority of our high-quality DNA controls, includingTissue DNA controls are extracted from normal, disease-free tissue sensitivity controls and panels, are supplied in aliquots of 100 Land are tested extensively to ensure quality and reproducibility of your and are adjusted to a final concentration of 200 g/mL in 1/10 TE test results. IVS-0000 Polyclonal Control DNA consists of genomic DNA (1 mM Tris- HCl (pH 8.0), 0.1 mM EDTA). This diluent providesisolated from the tissue of normal human tonsils. This control represents sufficient buffering capacity and EDTA to protect the DNA withoutan excellent negative control for gene rearrangements, chromosome interfering with the Mg 2+concentrations required for robusttranslocations, and mutation tests and is included in all of our PCR amplification reactions. DNA-based assay kits. This DNA is supplied at a volume of100 L and at a concentration of 200 g/mL. Catalog # Description1364-092-0010 IVS-0000 Polyclonal Control DNA*'