b'Table of ContentsIntroductionLetter to Our Colleagues2 Gel and Capillary - Research Use Only (RUO) Assays94Board of Directors4 IGH + IGK B-Cell Clonality Assays96Executive Leadership Team6 IGH Gene Rearrangement Assays98Best-in-Class Assays & Reagents8 IGH Gene Clonality Assays100LabPMM Clinical Lab Services10 IGK Gene Clonality Assays102Streamlined CDx Partnerships12 IGL Gene Clonality Assays104Global Distributor Network14 TCRB + TCRG T-Cell Clonality Assays106TCRB Gene Clonality Assays108Background T-Cell Receptor Gamma Gene Rearrangement Assay 2.0110Introduction16 T-Cell Receptor Gamma Gene Rearrangement Assays112Test Algorithm for Suspect Lymphoproliferations17 TCRG Gene Clonality Assays114TCRD Gene Clonality Assays116Next-Generation Sequencing (NGS)BCL1/JH Translocation Assay118LymphoTrack Dx Assays18 BCL2/JH t(14;18) Translocation Assay120BCL2/JH Translocation Assay122LymphoTrack Dx IGHV Leader Somatic Hypermutation Assay20 BCR/ABL t(9;22) Translocation Assays124LymphoTrack Dx IGH FR1/2/3 Assays22 PML/RARa t(15;17) Translocation Assays126LymphoTrack Dx IGK Assays26 IGH Somatic Hypermutation Assays v2.0128LymphoTrack Dx TRG Assays28 FLT3 Mutation Assays130LymphoTrack Dx TRB Assays30LymphoTrack Dx Bioinformatics Software32 Analyte Specific ReagentsAnalyte Specific Reagents132LymphoTrack - Research Use Only (RUO) Assays34LymphoTrack IGHV Leader Somatic Hypermutation Assay36 Controls, Reagents, and Enzymes LymphoTrack IGH FR1/FR2/FR3 Assays38 Overview134LymphoTrack IGK Assays42 DNA Controls136LymphoTrack TRG Assays44 Low Positive Controls140LymphoTrack TRB Assays46 Internal Controls139LymphoTrack Bioinformatics Software48 RNA Controls142Control Panels144LymphoTrack MRD Solution - Research Use Only (RUO) 50 Master Mix Controls148LymphoTrack Minimal Residual Disease (MRD) Software52 Custom Products LymphoTrack B-cell & T-cell Low Positive Controls54LymphoQuant B-cell & T-cell Internal Control55 Custom Products150Gel and Capillary ReferenceIdentiClone Assays56 Clonality Testing Workflow Methods153IGH + IGK B-Cell Clonality Assays58 Illumina MiSeq Workflow Summary154IGH Gene Clonality Assays60 Thermo Fisher Scientific Ion S5 PGM Workflow Summary155IGK Gene Clonality Assays62 Next-Generation Sequencing Menu156IGL Gene Clonality Assays64 Gel and Capillary Electrophoresis Menu157TCRB + TCRG T-Cell Clonality Assays66 Common Technical Support Questions158TCRB Gene Clonality Assays68 Recent Poster Abstracts162T-Cell Receptor Gamma Gene Rearrangement Assay 2.070 Product ListTCRG Gene Clonality Assays72TCRD Gene Clonality Assays74 Product List by Catalog Number164BCL1/JH Translocation Assay76BCL2/JH Translocation Assay78 IndexAlphabetical Index167LeukoStrat Assays80FLT3 Mutation Assay - Gel Detection82FLT3 Mutation Assay 2.0 - ABI Fluorescence Detection84 CDx FLT3 Mutation Assay (IVD) - USA86CDx FLT3 Mutation Assay (CE-marked)88CDx FLT3 Mutation Assay - AUS90CDx FLT3 Mutation Assay - Japan92'