b'MRD TestsTest Name used to identify DNA sequences specific to previously IGK MRD Clonality Assayidentified clonal rearrangements detected at diagnosis. Bioinformatics tools facilitate the detection of these specific sequences present at MRD levels up to 1 x 10 -6with sufficient Assay Type DNA input.Next-Generation Sequencing (NGS)The assay typically requires a sample taken at diagnosis as For Research Use Only well as the post-treatment follow-up samples. If the patient This test is performed by using the LymphoTrack Assayhas previously been tested by LabPMM for IGK clonality, no from Invivoscribe. Data is analyzed using the LymphoTrackdiagnostic sample is needed. MRD Software (RUO). Indications for TestingMethod Descriptiondentify tumor-specific markers for post-treatment ITo track and identify previously detected IGK clonalmonitoring sequences in post-treatment follow-up samples, a multiplexMonitor and evaluate disease recurrencemaster mix targeting the conserved V, J, C and kappa deleting element (K de ) regions is used for PCR amplification. Next-generation sequencing of the PCR products is Interpretation TurnaroundSpecimenShippingSpecimen Time Requirements Conditions StabilityAn interpretive5 to 14 1-3 mL of peripheral Ambient or Cool; 2-8 C up report will bebusiness days blood in EDTA do not freezeto 7 days priorissued indicating0.25-1 mL of bone marrow (peripheral blood orto testingwhether IGK MRDin EDTAbone marrow) was detectedAmbient or frozen on 700-3500 ng of previously isolated DNA dependingdry ice (isolated DNA) on level of sensitivity requiredLabPMM Services Catalog 2021|43'