b'ClonalityTestsTest Name used to identify DNA sequences specific to clonal gene TRB Clonality Assayrearrangements. Bioinformatics tools facilitate the characterization of sequences present at greater than2.5% of the population. These sequences can be used to Assay Type track specific clonal populations.Next-Generation Sequencing (NGS) Indications for TestingThis test is performed by using the LymphoTrack or Identify clonality in atypical lymphoproliferative LymphoTrack Dx Assay from Invivoscribe.disordersSupport a differential diagnosis between reactiveMethod Description lesions and hematologic malignanciesFor detection of the vast majority of TRB geneAssign presumptive lineage in mature monoclonalrearrangements, a multiplex master mix targetinglymphoproliferative disordersthe V, J and D regions is used for PCR amplification.Monitor and evaluate disease recurrenceNext-generation sequencing of the PCR products is Interpretation TurnaroundSpecimenShippingSpecimen Time Requirements Conditions StabilityAn interpretive report will be5 to 10 1-3 mL of peripheralAmbient or2-8 C up issued indicating whetherbusiness daysblood in Heparin, Cool; do notto 7 days prior evidence of clonality wasEDTA or ACD freeze (peripheralto testing detected. The report further0.25-1 mL of boneblood or bone provides a summary of the marrow) top 5 merged sequences,marrow in Heparin, including the % total reads, EDTA or ACD Ambient or 500 ng of previouslyfrozen on dry ice the rearrangement class and the sequence. isolated DNA(isolated DNA)LabPMM Services Catalog 2021|31'