b'Gel and Capillary Electrophoresis MenuInvivoscribe offers assays that can be analyzed using twoApplied Biosystems (ABI) platforms e.g. 3130, 3500, 3500xL, 3500xL conventional methods of fragment analysis: gel electrophoresis orDx. Fragment analysis by capillary electrophoresis offers the ability capillary electrophoresis. to detect fragments with a high level of accuracy and analytical sensitivity and allows for greater sample throughput comparedGel electrophoresis kits offer a comparatively easy and inexpensiveto gel detection methods. In addition, capillary electrophoresis solution for clonality, translocation, and mutational testing anddetection often facilitates a more objective interpretation of results are often the method of choice for laboratories new to usingthan gel-based detection.these methods and techniques. PCR products are analyzed using non-denaturing polyacrylamide gels (PAGE) and often require aThe table below summarizes which detection methods are available heteroduplex step for resolution of generated amplicons. for our clonality, translocation and FLT3 mutation assays either as RUO, CE-IVD, or IVD.Capillary electrophoresis kits are supplied with fluorescently labeled primers, allowing the resulting PCR products to be analyzed on CE-Marked IVD Assays Gel ABIIdentiClone IGH + IGK B-Cell Clonality Assay AVAILABLEAVAILABLE IdentiClone IGH Gene Clonality Assay AVAILABLEAVAILABLE IdentiClone IGK Gene Clonality Assay AVAILABLEAVAILABLE IdentiClone IGL Gene Clonality Assay AVAILABLEAVAILABLE IdentiClone TCRB Gene Clonality Assay AVAILABLEAVAILABLE IdentiClone T-Cell Receptor Gamma Gene Rearrangement Assay 2.0 NOT AVAILABLE AVAILABLE IdentiClone TCRD Gene Clonality Assay AVAILABLEAVAILABLE IdentiClone BCL1/J HTranslocation Assay AVAILABLENOT AVAILABLEIdentiClone BCL2/J HTranslocation Assay AVAILABLENOT AVAILABLELeukoStrat FLT3 Mutation Assay AVAILABLE NOT AVAILABLELeukoStrat FLT3 Mutation Assay 2.0 NOT AVAILABLE AVAILABLELeukoStrat CDx FLT3 Mutation Assay (CE-marked) NOT AVAILABLE AVAILABLEIVD Assays Gel ABILeukoStrat CDx FLT3 Mutation Assay IVD (USA)NOT AVAILABLE AVAILABLELeukoStrat CDx FLT3 Mutation Assay (AUS)NOT AVAILABLE AVAILABLELeukoStrat CDx FLT3 Mutation Assay (JP) NOT AVAILABLE AVAILABLELeukoStrat CDx FLT3 Mutation Assay (CE-IVD) NOT AVAILABLE AVAILABLEResearch Use Only (RUO) Assays Gel ABIFLT3 Mutation Assay AVAILABLE AVAILABLEIGH + IGK B-Cell Clonality Assay AVAILABLEAVAILABLE IGH Gene Rearrangement Assay AVAILABLEAVAILABLE IGH Gene Clonality Assay AVAILABLEAVAILABLE IGH Somatic Hypermutation Assay v2.0 AVAILABLEAVAILABLE IGL Gene Clonality Assay AVAILABLEAVAILABLE TCRB Gene Clonality Assay AVAILABLEAVAILABLE T-Cell Receptor Gamma Gene Rearrangement Assay AVAILABLEAVAILABLE T-Cell Receptor Gamma Gene Rearrangement Assay 2.0 AVAILABLE AVAILABLE TCRD Gene Clonality Assay AVAILABLEAVAILABLE BCL1/J HTranslocation Assay AVAILABLENOT AVAILABLEBCL2/J HTranslocation Assay AVAILABLENOT AVAILABLEBCL2/J Ht(14;18) Translocation Assay AVAILABLENOT AVAILABLEBCR/ABL t(9;22) Translocation Assay AVAILABLEAVAILABLE PML/RAR t(15;17) Translocation Assay AVAILABLEAVAILABLE CE-marked assays are in vitro diagnostic products and are not available for sale or use within North America. IVD assays are in vitro diagnostic products, and are available for sale or use in regions indicated.Invivoscribe 2021|155'