b'Hematological Test MenuDiseases Gene Rearrangement Translocation MutationsRecommended IGHIGHIGKIGLIGHVTRBTRDTRGIGH-IGH-BCR-PMLFLT3NPM1 Primary Test V H- J H D H- J H SHMBCL1BCL2 ABL1*RAR* Recommended (CCND1)Secondary TestMarginal Zone Lymphoma(MZL), extranodal 12,13,2788% 58% 84% 29% 23% 10% 16% Marginal Zone Lymphoma(MZL), nodal 13100% 30% 80% 30% 10% 20% 10% Mantle Cell Lymphoma (MCL) 2,6,7,12,13,27,37100% 11% 100% 44% * 9% 4% 11% 75%Follicular Lymphoma (FL) 3,7,12,13,27,2884% 19% 84% 21% 6% 5% 2% 90%Diffuse Large B-cell Lymphoma80% 30% 80% 28% 21% 14% 15% 30%(DLBCL) 3,12,13,27Multiple Myeloma (MM) and other Plasma Cell Neoplasms (PCN) 2,9,10,20,2584% 60% 57% 97% 20% Chronic Lymphocytic Leukemia (CLL) 11,12,13,15,23,27,35100% 43% 100% 30% * 25% 12% 18% Lymphoid/ LymphomaB-cell Acute LymphoblasticLeukemia (B-ALL) 4,12,14,19,21,22,27,29,30,31,32,33,3496% 57% 95% 20% 81% 86% 75% 30%Suspect B-cell Proliferations 12,26,27,3393% 93% 90% 40% 20% 20%Peripheral T-cell Lymphoma35% 4% 2% 98% 94%(PTCL) 12,13,14,24T-cell Acute Lymphoblastic Leukemia (T-ALL) 12,14,21,22,29,3124% 25% 4% 92% 68% 95% Angioimmunoblastic T-cellLymphoma (AILT) 12,13,1419% 11% 30% 5% 99% 35% 92%Adult T-cell Leukemia/Lymphoma 3997% 96% Anaplastic Large-Cell Lymphoma (ALCL) 12,13,1474% 12% 74%T-cell Prolymphocytic Leukemia (T-PLL) 12,13,143% 3% 3% 3% 100% 6% 94% T-cell Large Granular Lymphocytic Leukemia (T-LGL Leukemia) 12,13,144% 4% 97% 29% 96% Suspect T-Cell Proliferations 12,26,4010% 10% 90% 11% 90%Acute Myeloid Leukemia (AML) 8,1633% 64%Acute Promyelocytic Leukemia (APL) 1,5,16,1790%Myeloid Chronic Myeloid Leukemia (CML) 7,18,19,21,3887%Myeloproliferative Neoplasms (MPNs) 38 10%Note: The percentage of samples within a given disease category were detected using each gene target. Percentages indicate the highest referenced value.22'