PRODUCTS

Next Generation Sequencing (NGS)
Clonality Solutions

LymphoTrack Flex Assays
Order LymphoTrack Flex

Objective B- & T-cell clonality and ultra-high sensitivity (UHS) measurable residual disease (MRD) testing

ASSAYS ›

Streamlined PCR-based assay kits for detecting and tracking B- and T-cell clonality. Available in standard and flex formats to fit laboratories of different sizes and throughput needs.

SOFTWARE ›

Desktop and enterprise bioinformatic tools that streamline data analysis. As a companion to LymphoTrack Assays, they turn raw sequencing output into clear, actionable data. 

CONTROLS ›

Spike-in and run-validity controls that confirm assay sensitivity and enable accurate, low frequency clonal calls, plus quantitative tracking of clonal populations.

Standardized, Scalable NGS Workflow for Clonality, Somatic Hypermutation, and UHS MRD Testing

Scaling testing should not mean sacrificing sensitivity or confidence in results.  LymphoTrack Flex enables one standardized solution covering both immunoglobulin (Ig) and T-cell receptors (TCR), delivering objective, binary (detect or not-detected results) that labs can trust. Automation-ready chemistry and flexible DNA input give labs the flexibility to scale and bring testing in-house without compromising quality. 

LymphoTrack Flex Assay Targets

IGHV Leader

IGH FR1

IGH FR2

IGH FR3

IGK

TRB

TRG

Automation-Ready Clonal Analysis Across ALL, CLL, Multiple Myeloma, and Lymphoma

LymphoTrack Flex matches a lab’s needs as they evolve, supporting the same workflow across multiple sequencing platforms, including MiSeq, MiSeq i100, and NextSeq instruments.

See What Sets Flex Apart

Multiplexing Flexibility

Target amplification is decoupled from indexing, so multiple targets can be run together in the same instrument run, reducing per-sample cost and increasing throughput.

Consolidated Testing

Clonality, SHM, and MRD tracking on a single, unified solution; no need to validate and maintain both NGS and capillary electrophoresis platforms.

Operational Efficiency

Automation-ready chemistry with flexible DNA input (50-200 ng) with higher DNA input supporting enhanced MRD sensitivity.

Built to Scale

The LymphoTrack workflow is designed to support the latest sequencing platforms, paired with enterprise software built for automated analysis and Laboratory Information Management Systems (LIMS) integration.

LymphoTrack Standard vs. Flex: Compare NGS Workflows

LymphoTrack (Standard) LymphoTrack Flex
PCR Workflow 1-step 2-step (amplification separate from indexing)
Automatable No Yes
DNA Input 50ng 50 ng – 200 ng
Sensitivity Up to 1 x 10-6 Up to 1 x 10-6
Sequencing Platform Illumina,® MiSeqTM, MiSeqTM i100, Thermo Fisher® Ion S5/PGMTM Illumina® MiSeqTM, MiSeq i100, NextSeq 1000/2000
Software Enterprise or desktop analysis Enterprise or desktop analysis
LymphoTrack (Standard)

Software Built for High-Throughout Clonality and MRD Analysis

LymphoTrack Enterprise Software is a centralized solution built for high-throughput labs, pairing directly with the LymphoTrack and LymphoTrack Flex assays to remove subjective interpretation from the reporting process. Our architecture guarantees that updates will never disrupt your existing server environment, so your lab can scale without re-validating with every software update.

  • Full control of your data, safely on-premises
  • Automated, high-throughput analysis pipelines
  • Bioinformatician-friendly

For desktop implementation, LymphoTrack Software offers the same intuitive analysis for the original LymphoTrack Assay and new Flex Assays; no bioinformatics expertise required. Outputs include raw data and PDF reports with graphic visualizations.

LymphoTrack Enterprise Software
LymphoTrack Desktop Software

Validate Every Run with LymphoQuant® & LymphoTrack MRD Controls

Confident results start with a validated run. LymphoTrack NGS solutions offer two control types that support the sensitivity and reproducibility accurate results depend on. LymphoQuant Internal Controls enable accurate MRD quantification and tracking over time, while LymphoTrack low positive controls confirm each run can reliably detect low-level clonal B- and T-cell rearrangements.

MRD Controls

Find the Right NGS Clonality Solution for Your Lab

From standard-volume testing to high-throughput automation, LymphoTrack pairs high-sensitive assays and powerful software built for where your lab is today and where it’s headed.

Contact our Team

*For RESEARCH USE ONLY. Not for use in diagnostic procedures.